Identification of Potential New Genes Related to the SREBP Pathway in Xanthophyllomyces dendrorhous.

ABSTRACT: The sterol regulatory element-binding protein (SREBP) pathway is an integral cellular mechanism that regulates lipid homeostasis, in which transcriptional activator SREBPs regulate the expression of various genes. In the carotenogenic yeast Xanthophyllomyces dendrorhous, Sre1 (the yeast SREBP homolog) regulates lipid biosynthesis and carotenogenesis, among other processes. Despite the characterization of several components of the SREBP pathway across various eukaryotes, the specific elements of this pathway in X. dendrorhous remain largely unknown. This study aimed to explore the potential regulatory mechanisms of the SREBP pathway in X. dendrorhous using the strain CBS.cyp61^- as a model, which is known to have Sre1 in its active state under standard

SUBMITTER: Venegas M 

PROVIDER: S-EPMC11274570 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature