Diet and the Gut Microbiome as Determinants Modulating Metabolic Outcomes in Young Obese Adults.

ABSTRACT: Obesity, along with metabolic disorders such as dyslipidemia and insulin resistance, increases the risk of cardiovascular disease, diabetes, various cancers, and other non-communicable diseases, thereby contributing to higher mortality rates. The intestinal microbiome plays a crucial role in maintaining homeostasis and influencing human metabolism. This study enrolled 82 young obese individuals, who were stratified into groups with or without metabolic disturbances. No significant differences in the alpha or beta diversity of the microbiota were observed among the groups. Insulin resistance was characterized by an increase in the number of Adlercreutzia and Dialister as well as a decrease in Collinsella, Coprococcus and Clostridiales. The dyslipidemia and

SUBMITTER: Livantsova EN 

PROVIDER: S-EPMC11275099 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature