Visual system structural and functional connections during face viewing in body dysmorphic disorder.

ABSTRACT:

Background

Individuals with body dysmorphic disorder (BDD) perceive distortions in their appearance, which could be due to imbalances in global and local visual processing. The vertical occipital fasciculus connects dorsal and ventral visual stream regions, integrating global and local information, yet the role of this structural connection in BDD has not been explored. Here, we investigated the vertical occipital fasciculus's white matter microstructure in those with BDD and healthy controls and tested associations with psychometric measures and effective connectivity while viewing their face during fMRI.

Methods

We analyzed diffusion MRI and fMRI data in 17 unmedicated adults with BDD and 21 healthy controls. For diffusion MRI, bundle-specific analysis was performed, enabl

SUBMITTER: Wong WW 

PROVIDER: S-EPMC11275846 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature