Predelivery Haemostatic Biomarkers in Women with Non-Severe Postpartum Haemorrhage.

ABSTRACT: Background: Postpartum haemorrhage (PPH) is a frequent complication of childbirth that is difficult to predict. Predelivery coagulation biomarkers may help to guide preventive strategies. Our objective was to evaluate the association of predelivery haemostatic biomarkers with non-severe PPH. Methods: A nested case-control study was conducted within the « Study of Biological Determinants of Bleeding Postpartum » in order to compare different haemostatic biomarkers in plasma from pregnant women with non-severe PPH (cases) and controls without PPH matched for age, body mass index, term, and mode of delivery. Blood was collected at entry in the delivery room. Global haemostatic assays (thrombin generation assay (TGA) and plasmin generation assay (PGA)) were then performed on fres

SUBMITTER: de Moreuil C 

PROVIDER: S-EPMC11277716 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature