A Comprehensive Review of Biologics in Phase III and IV Clinical Trials for Atopic Dermatitis.

ABSTRACT: Atopic dermatitis (AD) is a skin condition characterized by significant challenges and a substantial deterioration in the life quality for affected patients. The therapeutic landscape for AD has witnessed a transformative shift with the emergence of biologic therapies. Our focus centers on biologics currently undergoing phase III and IV clinical trials, deeming them to hold the highest potential for significant clinical relevance. To identify biologic drugs under development in phase III and IV clinical trials, we searched ClinicalTrials.gov. Additional relevant trials were identified through JapicCTI/ Japan Registry of Clinical Trials (jRCT) with a citation search. A search in MEDLINE and EMBASE was performed. There have been 76 clinical trials identified concerning biologic drugs: dupilu

SUBMITTER: Waligora-Dziwak K 

PROVIDER: S-EPMC11277805 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature