Outcomes associated with postoperative cognitive dysfunction: a systematic review and meta-analysis.

ABSTRACT:

Background

Postoperative cognitive dysfunction (POCD) manifests as a subtle decline in cognition, potentially leading to unfavourable postoperative outcomes. We explored the impact of POCD on physical function, length of hospital stay (LOS), dementia and mortality outcomes.

Methods

PubMed and Scopus were searched until May 2023. All studies of major surgical patients that assessed POCD and outcomes of interest were included. POCD effects were stratified by surgery type (cardiac and noncardiac) and time of POCD assessment (<30 and ≥30 days postsurgery).

Results

Of 2316 studies, 20 met the inclusion criteria. POCD was not associated with functional decline postsurgery. Patients who experienced POCD postcardiac surgery had an increased relative risk (RR) of death of 2.04

SUBMITTER: Suraarunsumrit P 

PROVIDER: S-EPMC11277860 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature