Comparative Analysis of Phlebotomus argentipes Vector of Leishmaniasis in India and Sri Lanka.

ABSTRACT: Phlebotomus argentipes is the predominant sandfly vector of leishmaniasis in the Indian subcontinent. India and Sri Lanka primarily report visceral and cutaneous leishmaniasis caused by Leishmania donovani. We compared Ph. argentipes from two locations, focusing on its morphological, molecular, and salivary protein characteristics. Sandflies were captured using CDC light traps and cattle-baited net traps. Species identification and morphological comparisons were carried out using standard taxonomic keys. DNA extracted from 12 Sri Lankan sandfly samples was PCR-amplified and sequenced for the variable region of Cytochrome oxidase subunit I. Existing DNA sequences of India from GenBank were utilized for a phylogenetic analysis between Sri Lanka and India. Salivary protei

SUBMITTER: Piyasiri SB 

PROVIDER: S-EPMC11278908 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature