Shiga Toxin-Producing Escherichia coli Strains from Romania: A Whole Genome-Based Description.

ABSTRACT: The zoonotic Shiga toxin-producing Escherichia coli (STEC) group is unanimously regarded as exceptionally hazardous for humans. This study aimed to provide a genomic perspective on the STEC recovered sporadically from humans and have a foundation of internationally comparable data. Fifty clinical STEC isolates, representing the culture-confirmed infections reported by the STEC Reference Laboratory between 2016 and 2023, were subjected to whole-genome sequencing (WGS) analysis and sequences were interpreted using both commercial and public free bioinformatics tools. The WGS analysis revealed a genetically diverse population of STEC dominated by non-O157 serogroups commonly reported in human STEC infections in the European Union. The O26:H11 strains of ST21 lineage played a major role

SUBMITTER: Usein CR 

PROVIDER: S-EPMC11278934 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature