Evaluation of dynamic cerebrovascular autoregulation during liver transplantation.

ABSTRACT:

Background

Cerebrovascular autoregulation in patients with acute and chronic liver failure is often impaired, yet an intact autoregulation is essential for the demand-driven supply of oxygenated blood to the brain. It is unclear, whether there is a connection between cerebrovascular autoregulation during liver transplantation (LTX) and the underlying disease, and if perioperative anesthesiologic consequences can result from this.

Methods

In this prospective observational pilot study, data of twenty patients (35% female) undergoing LTX were analyzed. Cerebral blood velocity was measured using transcranial doppler sonography and was correlated with arterial blood pressure. The integrity of dynamic cerebrovascular autoregulation (dCA) was evaluated in the frequency domain throu

SUBMITTER: Wolpert BM 

PROVIDER: S-EPMC11280153 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature