Combinations and Temporal Associations Among Precursor Symptoms Before a First Episode of Psychosis.

ABSTRACT:

Background and hypothesis

Symptoms that precede a first episode of psychosis (FEP) can ideally be targeted by early intervention services with the aim of preventing or delaying psychosis onset. However, these precursor symptoms emerge in combinations and sequences that do not rest fully within traditional diagnostic categories. To advance our understanding of illness trajectories preceding FEP, we aimed to investigate combinations and temporal associations among precursor symptoms.

Study design

Participants were from PEPP-Montréal, a catchment-based early intervention program for FEP. Through semistructured interviews, collateral from relatives, and a review of health and social records, we retrospectively measured the presence or absence of 29 precursor symptoms, including

SUBMITTER: Paquin V 

PROVIDER: S-EPMC11283192 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature