Impact of a short-term Mediterranean diet intervention on plasma metabolites: a pilot study.

ABSTRACT:

Background

Dietary habits significantly influence the risks of type 2 diabetes and cardiovascular disease. Through metabolomics, we've previously measured plasma metabolites to gauge dietary quality, introducing a healthy dietary metabolic signature (HDMS) linked to a decreased risk of future type 2 diabetes and coronary artery disease.

Objectives

To assess the impact of a 6-day dietary intervention on plasma metabolites and the HDMS.

Methods

Fifty-nine Swedish participants (71% women, mean age 69 years) underwent a 6-day Mediterranean diet (MD) intervention in Italy's Cilento region. All meals, crafted from local recipes and ingredients, were provided. Metabolite profiling pre- and post-intervention was conducted with a UHPLC-QTOF. Alterations in metabolite levels an

SUBMITTER: Smith E 

PROVIDER: S-EPMC11283393 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature