Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC.

ABSTRACT: Structural neuroimaging studies have identified a combination of shared and disorder-specific patterns of gray matter (GM) deficits across psychiatric disorders. Pooling large data allows for examination of a possible common neuroanatomical basis that may identify a certain vulnerability for mental illness. Large-scale collaborative research is already facilitated by data repositories, institutionally supported databases, and data archives. However, these data-sharing methodologies can suffer from significant barriers. Federated approaches augment these approaches by enabling access or more sophisticated, shareable and scaled-up analyses of large-scale data. We examined GM alterations using Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymous Computation, an open-source,

SUBMITTER: Rootes-Murdy K 

PROVIDER: S-EPMC11284501 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature