Interleukin-6 and Cardiovascular Events in Healthy Adults: MESA.

ABSTRACT:

Background

Elevated interleukin (IL)-6 levels have been linked to adverse outcomes in patients with and without baseline cardiovascular disease (CVD).

Objectives

The purpose of this study was to examine the association between circulating IL-6 levels and CVD events without baseline CVD across racial and ethnic groups.

Methods

We conducted an observational analysis utilizing the MESA (Multi-Ethnic Study of Atherosclerosis), a multicenter, prospective community-based study of CVD at baseline from four racial and ethnic groups. IL-6 levels were measured at the time of enrollment (visit 1) and were divided into 3 terciles. Patient baseline characteristics and outcomes, including all-cause mortality, CV mortality, heart failure, and non-CV mortality, were included. Cox pro

SUBMITTER: Khan MS 

PROVIDER: S-EPMC11284704 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature