Pharmacological non-hormonal treatment options for male infertility: a systematic review and network meta-analysis.

ABSTRACT:

Background

Male factor infertility affect up to 50% of couples unable to conceive spontaneously. Several non-hormonal pharmacological treatments have been proposed to boost spermatogenesis and increase chances of conception in men with infertility. Still, no clear evidence exists on the most effective treatment strategy.

Objective

We aimed to compare the effectiveness of non-hormonal pharmacological treatment options for men with infertility using a systematic review and network meta-analysis.

Methods

We searched MEDLINE, EMBASE, and CENTRAL until October 2023 for randomised/quasi-randomised trials that evaluated any non-hormonal pharmacological treatment options for men with idiopathic semen abnormalities or those with hypogonadism. We performed pairwise and network

SUBMITTER: Al Wattar BH 

PROVIDER: S-EPMC11285325 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature