Efficacy and safety of transcutaneous auricular vagus nerve stimulation for frequent premature ventricular complexes: rationale and design of the TASC-V trial.

ABSTRACT:

Background

Premature Ventricular Complexes (PVCs) are very common in clinical practice, with frequent PVCs (more than 30 beats per hour) or polymorphic PVCs significantly increasing the risk of mortality. Previous studies have shown that vagus nerve stimulation improves ventricular arrhythmias. Stimulation of the auricular distribution of the vagus nerve has proven to be a simple, safe, and effective method to activate the vagus nerve. Transcutaneous au ricular vagus nerve stimulation (taVNS) has shown promise in both clinical and experimental setting for PVCs; however, high-quality clinical studies are lacking, resulting in insufficient evidence of efficacy.

Methods

The study is a prospective, randomized, parallel-controlled trial with a 1:1 ratio between the two groups. Pa

SUBMITTER: Liu Y 

PROVIDER: S-EPMC11285463 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature