Effect of resistance training on physical function during chemotherapy in colon cancer.

ABSTRACT:

Background

The decline of physical function during chemotherapy predicts poor quality of life and premature death. It is unknown if resistance training prevents physical function decline during chemotherapy in colon cancer survivors.

Methods

This multicenter trial randomly assigned 181 colon cancer survivors receiving postoperative chemotherapy to home-based resistance training or usual care control. Physical function outcomes included the short physical performance battery, isometric handgrip strength, and the physical function subscale of the Medical Outcomes Short-Form 36-item questionnaire. Mixed models for repeated measures quantified estimated treatment differences.

Results

At baseline, participants had a mean (SD) age of 55.2 (12.8) years; 67 (37%) were 60 year

SUBMITTER: Brown JC 

PROVIDER: S-EPMC11285783 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature