Imaging Assessments and Clinical Significance of Brain Frailty in Moyamoya Disease.

ABSTRACT:

Background and purpose

Imaging assessment of brain frailty in ischemic stroke has been extensively studied, while the correlation between brain frailty and Moyamoya disease remains obscure. This study aimed to investigate the imaging characteristics of brain frailty and its clinical applications in Moyamoya disease.

Materials and methods

This study included 60 patients with Moyamoya disease (107 hemispheres). All patients were divided into stroke and nonstroke groups based on clinical symptoms and imaging findings. The modified brain frailty score was adapted to consider 4 imaging signs: white matter hyperintensity, enlargement of perivascular space, old vascular lesions, and cerebral microbleed. The relative CBF of the MCA territory was quantified using pseudocontinuous art

SUBMITTER: Wang L 

PROVIDER: S-EPMC11286025 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature