Early stress exposure on zebrafish development: effects on survival, malformations and molecular alterations.

ABSTRACT: The effects of stress during early vertebrate development can be especially harmful. Avoiding stressors in fish larvae is essential to ensure the health of adult fish and their reproductive performance and overall production. We examined the consequences of direct exposure to successive acute stressors during early development, including their effects on miR-29a and its targets, survival, hatching and malformation rates, larval behaviour and cartilage and eye development. Our aim was to shed light on the pleiotropic effects of early-induced stress in this vertebrate model species. Our results showed that direct exposure to successive acute stressors during early development significantly upregulated miR-29a and downregulated essential collagen transcripts col2a1a, col6a2 and col11a1a, decr

SUBMITTER: Valcarce DG 

PROVIDER: S-EPMC11286684 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature