Age-correlated changes in the canine oral microbiome.

ABSTRACT:

Introduction

Canine oral disease has been associated with significant changes in the oral microbiome rather than the presence or absence of individual species. In addition, most studies focus on a single age group of canines and as of yet, the relationship between canine microbiomes and age is poorly understood.

Methods

This study used a shotgun whole gene sequencing approach in tandem with the Aladdin Bioinformatics platform to profile the microbiomes of 96 companion dogs, with the sourmash-zymo reference database being used to perform taxonomic profiling.

Results

Findings showed significant age correlations among 19 species, including positive correlations among several Porphyromonas species and a negative correlation with C. steedae. Although a signif

SUBMITTER: Kislik G 

PROVIDER: S-EPMC11287893 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature