Serotonergic amplification of odor-evoked neural responses maps onto flexible behavioral outcomes.

ABSTRACT: Behavioral responses to many odorants are not fixed but are flexible, varying based on organismal needs. How such variations arise and the role of various neuromodulators in achieving flexible neural-to-behavioral mapping is not fully understood. In this study, we examined how serotonin modulates the neural and behavioral responses to odorants in locusts (Schistocerca americana). Our results indicated that serotonin can increase or decrease appetitive behavior in an odor-specific manner. On the other hand, in the antennal lobe, serotonergic modulation enhanced odor-evoked response strength but left the temporal features or the combinatorial response profiles unperturbed. This result suggests that serotonin allows for sensitive and robust recognition of odorants. Nevertheless, the un

SUBMITTER: Bessonova Y 

PROVIDER: S-EPMC11288630 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature