Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations.
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SUBMITTER: Selvavinayagam ST
PROVIDER: S-EPMC11289243 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature
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Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations.
Selvavinayagam Sivaprakasam T ST Sankar Sathish S Yong Yean K YK Murugesan Amudhan A Suvaithenamudhan Suvaiyarasan S Hemashree Kannan K Rajeshkumar Manivannan M Kumaresan Anandhazhvar A Pandey Ramendra P RP Shanmugam Saravanan S Arthydevi Parthiban P Kumar Masilamani Senthil MS Gopalan Natarajan N Kannan Meganathan M Cheedarla Narayanaiah N Tan Hong Y HY Zhang Ying Y Larsson Marie M Balakrishnan Pachamuthu P Velu Vijayakumar V Byrareddy Siddappa N SN Shankar Esaki M EM Raju Sivadoss S
Scientific reports 20240730 1
In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence. We characterized the clinical profile, and genetic changes in JN.1, an emerging SARS-CoV-2 variant of interest. Whole genome sequencing was performed on SARS-CoV-2 positive clinical specimens, followed by sequence analysis. Mutations within the spike protein sequences were analysed and compared with the previously reported lineages and sub ...[more]
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Project description: Not available
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