Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex.

ABSTRACT: Time courses of neural responses underlie real-time sensory processing and perception. How these temporal dynamics change may be fundamental to how sensory systems adapt to different perceptual demands. By simultaneously recording from hundreds of neurons in mouse primary visual cortex, we examined neural population responses to visual stimuli at sub-second timescales, during different behavioural states. We discovered that during active behavioural states characterised by locomotion, single-neurons shift from transient to sustained response modes, facilitating rapid emergence of visual stimulus tuning. Differences in single-neuron response dynamics were associated with changes in temporal dynamics of neural correlations, including faster stabilisation of stimulus-evoked changes in the str

SUBMITTER: Horrocks EAB 

PROVIDER: S-EPMC11289260 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature