Medication Optimization Protocol Efficacy for Geriatric Inpatients: A Randomized Clinical Trial.

ABSTRACT:

Importance

There is currently no consensus on clinically effective interventions for polypharmacy among older inpatients.

Objective

To evaluate the effect of multidisciplinary team-based medication optimization on survival, unscheduled hospital visits, and rehospitalization in older inpatients with polypharmacy.

Design, setting, and participants

This open-label randomized clinical trial was conducted at 8 internal medicine inpatient wards within a community hospital in Japan. Participants included medical inpatients 65 years or older who were receiving 5 or more regular medications. Enrollment took place between May 21, 2019, and March 14, 2022. Statistical analysis was performed from September 2023 to May 2024.

Intervention

The participants were randomly assig

SUBMITTER: Ie K 

PROVIDER: S-EPMC11289701 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature