Causal Association of Arterial Stiffness With the Risk of Chronic Kidney Disease.

ABSTRACT:

Background

Previous studies on the direction of the association between arterial stiffness (AS) and chronic kidney disease (CKD) were inconsistent, leaving a knowledge gap in understanding the temporal sequence of the association.

Objectives

This study sought to assess the temporal and longitudinal relationship between AS and CKD.

Methods

The temporal relationship between AS measured by brachial ankle pulse wave velocity and CKD measured by estimated glomerular filtration rate (eGFR) was analyzed among 7,753 participants with repeated examinations in the Kailuan study using cross-lagged panel analysis. The longitudinal associations of AS status and vascular aging (VA) phenotype with incident CKD were analyzed among 10,535 participants.

Results

The adjusted cros

SUBMITTER: Tian X 

PROVIDER: S-EPMC11291385 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature