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Risk factors for distant metastasis and prognosis of the penile cancer with distant metastasis.


ABSTRACT:

Background

Penile cancer (PC) is a rare malignant tumor, whose distant metastasis (DM) is associated with the poorest outcomes. The risk factors associated with DM and prognosis of the PC with DM remain elusive. This study was aimed at investigating risk factors associated with DM and constructing prediction models of PC with DM.

Methods

This study analyzed data from the Surveillance, Epidemiology, and End Results (SEER) database over a period of 2000-2020, including clinical characteristics such as age, marital status, tumor size, Tumor Node Metastasis (TNM) staging, and treatment information. Utilizing univariate and multivariate logistic regression, alongside cox regression analysis, we identified independent risk factors for DM and prognosis in the total cases and the ca

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC11291400 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature