Brain invasion of bovine coronavirus: molecular analysis of bovine coronavirus infection in calves with severe pneumonia and neurological signs.

ABSTRACT:

Importance

Although the role of bovine coronavirus (BCoV) in calf diarrhea and respiratory disorders is well documented, its contribution to neurological diseases is unclear.

Objective

This study conducted virological investigations of calves showing diarrhea and respiratory and neurological signs.

Methods

An outbreak of diarrhea, respiratory, and neurological disorders occurred among the 12 calves in July 2022 in Istanbul, Türkiye. Two of these calves exhibited neurological signs and died a few days after the appearance of symptoms. One of these calves was necropsied and analyzed using molecular and histopathological tests.

Results

BCoV RNA was detected in the brain, lung, spleen, liver, and intestine of the calf that had neurological signs by real-time revers

SUBMITTER: Yilmaz SG 

PROVIDER: S-EPMC11291437 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature