Ontology highlight
ABSTRACT: Background
Skeletal muscle mass is determined predominantly by feeding-induced and activity-induced fluctuations in muscle protein synthesis (MPS). Older individuals display a diminished MPS response to protein ingestion, referred to as age-related anabolic resistance, which contributes to the progression of age-related muscle loss known as sarcopenia.Objectives
We aimed to determine the impact of consuming higher-quality compared with lower-quality protein supplements above the recommended dietary allowance (RDA) on integrated MPS rates. We hypothesized that increasing total protein intake above the RDA, regardless of the source, would support higher integrated rates of myofibrillar protein synthesis.Methods
Thirty-one healthy older males (72 ± 4 y) consumed a cont
SUBMITTER: McKendry J
PROVIDER: S-EPMC11291473 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature