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Inverse relationship between LDL-C/HDL-C ratio and atrial fibrillation in chronic kidney disease patients.


ABSTRACT: Atrial fibrillation (AF) is more prevalent in individuals with chronic kidney disease (CKD) compared to the general population. While a potential inverse correlation between lipid levels and AF has been proposed, it remains unclear if this relationship applies to CKD patients. This study examined the connection between the ratio of low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C) and the likelihood of AF in CKD patients. Data was gathered from 21,091 consecutive CKD patients between 2006 and December 31, 2015. We examined the link between the LDL-C/HDL-C ratio and AF in CKD patients through binary logistic regression, as well as various sensitivity and subgroup analyses. The dataset that backs up these analyses is available at: https://journals.plos

SUBMITTER: Guan M 

PROVIDER: S-EPMC11291658 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature