A new model for determining risk of male infertility from serum hormone levels, without semen analysis.

ABSTRACT: We investigated a screening method using only serum hormone levels and AI (artificial intelligence) predictive analysis. Among 3662 patients, numbers for NOA (non-obstructive azoospermia), OA (obstructive azoospermia), cryptozoospermia, oligozoospermia and/or asthenozoospermia, normal, and ejaculation disorder were 448, 210, 46, 1619, 1333, and 6, respectively. "Normal" was defined as semen findings normal according to the WHO (World Health Organization) Manual for Human Semen Testing of 2021. We extracted age, LH (luteinizing hormone), FSH (follicle stimulating hormone), PRL (prolactin), testosterone, E2 (estradiol), and T (testosterone)/E2 from medical records. A total motility sperm count of 9.408 × 10⁶ (1.4 ml × 16 × 10⁶/ml × 42%) was defined as the lower limit of

SUBMITTER: Kobayashi H 

PROVIDER: S-EPMC11291977 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature