Risk of diabetes mellitus in systemic lupus erythematosus: systematic review and meta-analysis.

ABSTRACT:

Objective

To investigate the risk of DM and evaluate the impact of SLE therapies on the risk of developing DM in patients with SLE.

Methods

Electronic database searches of PubMed, Embase, Cochrane Library and Web of Science were performed from inception to February 2023. Cohort and cross-sectional studies that analysed the risk of DM in patients with SLE were included. The associations between diabetes and antirheumatic agents, such as antimalarials and glucocorticoids, were analysed in cohort studies. Data were pooled using fixed- or random-effects meta-analysis to estimate pooled odd ratios (OR), relative risks (RR) and 95% confidence intervals (CIs). This study was registered with PROSPERO (CRD42023402774).

Results

A total of 37 studies (23 cross-sectional and 14 c

SUBMITTER: Etchegaray-Morales I 

PROVIDER: S-EPMC11292046 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature