Prostate Cancer Diagnosis Rates among Insured Men with and without HIV in South Africa: A Cohort Study.

ABSTRACT:

Background

Several studies have found lower prostate cancer diagnosis rates among men with human immunodeficiency virus (HIV; MWH) than men without HIV but reasons for this finding remain unclear.

Methods

We used claims data from a South African private medical insurance scheme (July 2017- July 2020) to assess prostate cancer diagnosis rates among men aged ≥ 18 years with and without HIV. Using flexible parametric survival models, we estimated hazard ratios (HR) for the association between HIV and incident prostate cancer diagnoses. We accounted for potential confounding by age, population group, and sexually transmitted infections (confounder-adjusted model) and additionally for potential mediation by prostatitis diagnoses, prostate-specific antigen testing, and prostate bi

SUBMITTER: Ruffieux Y 

PROVIDER: S-EPMC11292191 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature