Effect of gout and diabetic kidney disease on renal cancer development in Korea.

ABSTRACT:

Background

Chronic kidney disease (CKD) and gout are risk factors for renal cancer. We analysed the effects of comorbid diabetic kidney disease and gout on renal cancer.

Methods

This retrospective cohort study enrolled 847 884 patients with type 2 diabetes mellitus (T2DM) who underwent health assessments provided by the Korean National Health Insurance Service in 2009. Based on CKD occurrence (glomerular filtration rate <60 ml/min/1.73 m²) and gout (two outpatient visits or one hospitalization within 5 years), patients were classified into four groups: CKD^-Gout^- (87.5%), CKD^-Gout⁺ (2.5%), CKD⁺Gout^- (9.3%) and CKD⁺Gout⁺ (0.7%). Patients with incident renal cancer (International

SUBMITTER: Chung SM 

PROVIDER: S-EPMC11292222 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature