The relationship between serum 1,5-anhydroglucitol and adverse outcomes in acute coronary syndrome with and without chronic kidney disease patients.

ABSTRACT:

Purpose

Individuals with chronic kidney disease (CKD) face an elevated residual risk of cardiovascular events, but the relationship between this residual risk and 1,5-anhydroglucitol (1,5-AG) is uncertain. Our study aimed to examine the effect of 1,5-AG on major adverse cardiovascular events (MACEs) and all-cause mortality in acute coronary syndrome (ACS) individuals.

Methods

1253 ACS participants hospitalized were enrolled at Beijing Hospital between March 2017 and March 2020. All participants were classified into 2 groups based on their eGFR (60 ml/min/1.73 m²). The link between 1,5-AG and adverse outcome was investigated in non-CKD and CKD participants.

Results

CKD patients had reduced concentrations of 1,5-AG than those without CKD. Throughout a median

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11292232 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature