Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure.

ABSTRACT:

Importance

Approximately 40% of patients with heart failure (HF) who are eligible for cardiac resynchronization therapy (CRT) either fail to respond or are untreatable due to anatomical constraints.

Objective

To assess the safety and efficacy of a novel, leadless, left ventricular (LV) endocardial pacing system for patients at high risk for a CRT upgrade or whose coronary sinus (CS) lead placement/pacing with a conventional CRT system failed.

Design, setting, and participants

The SOLVE-CRT study was a prospective multicenter trial enrolling January 2018 through July 2022, with follow-up at 6 months. Data were analyzed from January 17, 2018, through February 15, 2023. The trial combined data from an initial randomized, double-blind study (n = 108) and a subsequent sing

SUBMITTER: Singh JP 

PROVIDER: S-EPMC11292567 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature