No immediate change in systemic cytokines following an eccentric muscle training session in people with multiple sclerosis.

ABSTRACT: Eccentric muscle contractions elicit distinct physiological responses, including modulation of the cytokine profile. Although relevant for rehabilitation, the effect of eccentric muscle training on the immune system has never been investigated in multiple sclerosis (MS). Examine the immediate cytokine response of interleukin-4 (IL-4), IL-6, IL-10, IL-17a, interferon-gamma, and tumor necrosis factor-alpha after a moderate eccentric training session in individuals with MS. Additionally, further investigate the association between systemic cytokine levels at rest and clinical measures of mobility and lower limb functional strength. Observational study. The first session included blood sampling for baseline cytokine measures. Subsequently, the participant completed a battery of clinical assess

SUBMITTER: Alt Y 

PROVIDER: S-EPMC11292683 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature