Rational Design and Evaluation of Photoactive Molecularly Imprinted Nanoparticles for Tetracycline Degradation Under Visible Light.

ABSTRACT: This work presents the use of photoactive molecularly imprinted nanoparticles (MINs) to promote antibiotic degradation under visible light irradiation. Prototype MINs for the model antibiotic tetracycline (TC) were developed using molecular dynamics simulations to predict the TC-binding capacity of seven pre-polymerization mixtures. The studied formulations contained varying proportions of functional monomers with diverse physicochemical profiles, namely N-isopropylacrylamide (NIPAM), N-tert-butylacrylamide (TBAM), acrylic acid (AA), and (N-(3-aminopropyl)methacrylamide hydrochloride) (APMA) and a constant ratio of the cross-linker N,N'-methylene-bis-acrylamide (BIS). Two monomer formulations showed markedly higher TC-binding capacities based on te

SUBMITTER: Garcia Y 

PROVIDER: S-EPMC11292816 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature