Associations between lifestyle-related risk factors and back pain: a systematic review and meta-analysis of Mendelian randomization studies.

ABSTRACT:

Background

Mendelian randomization (MR) studies have an advantage over conventional observational studies when studying the causal effect of lifestyle-related risk factors on back pain. However, given the heterogeneous design of existing MR studies on back pain, the reported causal estimates of these effects remain equivocal, thus obscuring the true extent of the biological effects of back pain lifestyle-risk factors.

Purpose

The purpose of this study was to conduct a systematic review with multiple meta-analyses on the associations between various lifestyle factors and low back pain.

Methods

We conducted a PRISMA systematic review and specifically included MR studies to investigate the associations between lifestyle factors-specifically, BMI, insomnia, smoking, alcoh

SUBMITTER: Guan J 

PROVIDER: S-EPMC11293147 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature