Evolution and improved outcomes in the era of multimodality treatment for extended pancreatectomy.

ABSTRACT: The evolution and outcomes of extended pancreatectomies at a single institute over 15 years are presented in this study. A retrospective analysis of the institutional database was performed from 2015 to 2022 (period B). Patients undergoing extended pancreatic resections, as defined by the International Study Group for Pancreatic Surgery, were included. Perioperative and survival outcomes were compared with data from 2007-2015 (period A). Regression analyses were used to identify factors affecting postoperative and long-term survival outcomes. A total of 197 (16.1%) patients underwent an extended resection in period B compared to 63 (9.2%) in period A. Higher proportions of borderline resectable (5 (18.5%) versus 51 (47.7%), P = 0.011) and locally advanced tumours (1 (3.7%) versus 24 (22.4%

SUBMITTER: Chaudhari VA 

PROVIDER: S-EPMC11293468 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature