Comparative efficacy of biologics for patients with inadequately controlled asthma: A network meta-analysis.

ABSTRACT:

Background

Few studies have evaluated the comparative efficacy of biologics for asthma. This network meta-analysis aimed to compare the efficacy of biologics.

Methods

This study included randomized controlled trials (RCTs) evaluating the efficacy of a biologic compared to a placebo or another biologic in patients with inadequately controlled asthma despite high-intensity treatment, published by January 6, 2022. Two researchers independently searched the PubMed, Embase, Web of Science, and Scopus and assessed the risk of bias using the Cochrane tool. The outcomes of interest were the annual asthma exacerbation rate (AER), forced expiratory volume per second before bronchodilator use (preBD FEV1), the asthma control questionnaire (ACQ), and asthma quality of life questionnaire

SUBMITTER: Kim H 

PROVIDER: S-EPMC11293571 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature