Sarcopenic obesity and health outcomes: An umbrella review of systematic reviews with meta-analysis.

ABSTRACT: Many studies support the idea that sarcopenic obesity (SO) could be considered a potential risk factor for negative health outcomes. These results have been inconsistent, and no umbrella reviews exist regarding this topic. Several databases until November 2023 were searched for systematic reviews with meta-analysis of observational studies (cross-sectional, case-control and prospective). For each association, random-effects summary effect sizes with correspondent 95% confidence intervals (CIs) were evaluated using the GRADE tool. Among the 213 papers initially screened, nine systematic reviews with meta-analysis were included, for a total of 384 710 participants. In cross-sectional and case-control studies, 30 different outcomes were analysed, and 18 were statistically significant. In any

SUBMITTER: Veronese N 

PROVIDER: S-EPMC11294015 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature