Selection for stress tolerance and longevity in Drosophila melanogaster have strong impacts on microbiome profiles.

ABSTRACT: There is experimental evidence that microbiomes have a strong influence on a range of host traits. Understanding the basis and importance of symbiosis between host and associated microorganisms is a rapidly developing research field, and we still lack a mechanistic understanding of ecological and genetic pressures affecting host-microbiome associations. Here Drosophila melanogaster lines from a large-scale artificial selection experiment were used to investigate whether the microbiota differ in lines selected for different stress resistance traits and longevity. Following multiple generations of artificial selection all selection regimes and corresponding controls had their microbiomes assessed. The microbiome was interrogated based on 16S rRNA sequencing. We found that the microbiome of f

SUBMITTER: Kristensen TN 

PROVIDER: S-EPMC11294339 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature