Comparison of antimicrobial therapy termination in febrile and afebrile patients with acute cholangitis after drainage.

ABSTRACT: The standard treatment duration for acute cholangitis (AC) involves a 4-7-day antimicrobial treatment post-biliary drainage; however, recent studies have suggested that a ≤ 2-3 days is sufficient. However, clinical practice frequently depends on body temperature as a criterion for discontinuing antimicrobial treatment. Therefore, in this study, we assessed whether patients with AC can achieve successful outcomes with a ≤ 7-day antimicrobial treatment, even with a fever, assuming the infection source is effectively controlled. We conducted a single-center retrospective study involving patients with AC, defined following the Tokyo Guidelines 2018 for any cause, who underwent successful biliary drainage and completed a ≤ 7-day antimicrobial treatment. Patients were categorized into the febril

SUBMITTER: Masuda S 

PROVIDER: S-EPMC11294559 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature