Long-range linkage disequilibrium events on the genome of dromedary camels as a signal of epistatic and directional positive selection.

ABSTRACT: The genome of dromedary camels has been subjected to various evolutionary forces, such as genetic admixture, natural positive selection, and epistatic selection. These forces are considered as main factors associated with the formation of long-range linkage disequilibrium (LRLD) events. We have analyzed whole-genome data of 56 dromedary camel samples from different geographical regions across the Arabian Peninsula for two main purposes: first, to assess the level of linkage disequilibrium, and second, to identify autosomal LRLD events. The analysis revealed a mean r ² value of 0.25 (±0.028) over the dromedary autosomes, with a continuous decay until reaching a plateau at inter-variant distances >400 kb. A total of 1847 LRLD events were identified within the dromeda

SUBMITTER: Bahbahani H 

PROVIDER: S-EPMC11295981 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature