Epilepsies with onset during the first year of life: A prospective study on syndromes, etiologies, and outcomes.

ABSTRACT:

Objective

Infantile seizures cause great concern for both doctors and parents. In addition to modern neuroimaging and genetics, clinical tools helpful in predicting the course of the disease are needed. We prospectively studied the incidence, electroclinical characteristics and etiologies of epilepsy syndromes with onset before the age of 12 months and looked for prognostic determinants of outcome by age 24 months.

Methods

From February 2017 through May 2019, we recruited all eligible infants diagnosed with epilepsy at our unit. Data on electroclinical studies, genetic investigations and drug response were gathered prospectively. The infants were given a structured neurological examination (Hammersmith Infantile Neurological examination [HINE] and Griffiths scales) at predet

SUBMITTER: Jonsson H 

PROVIDER: S-EPMC11296082 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature