Physiologically based trimester-specific serum ferritin thresholds for iron deficiency in US pregnant women.

ABSTRACT:

Abstract

Serum ferritin (SF) concentration is the most widely used indicator for iron deficiency (ID). During pregnancy, the World Health Organization recently recommended SF thresholds for ID of <15 μg/L for the first trimester of pregnancy, based on expert opinion, and made no recommendations for the second and third trimesters. We examined the relationship of SF with 2 independent indicators of the onset of iron-deficient erythropoiesis, hemoglobin and soluble transferrin receptor 1, in cross-sectional data from US National Health and Nutrition Examination Survey for 1999 to 2010 and 2015 to 2018. We included 1288 pregnant women aged 15 to 49 years and excluded women with inflammation or potential liver disease. We used restricted cubic spline (RCS) regression analysis to determ

SUBMITTER: Mei Z 

PROVIDER: S-EPMC11296244 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature