The role of functional emotion circuits in distinct dimensions of psychopathology in youth.

ABSTRACT: Several mental disorders emerge during childhood or adolescence and are often characterized by socioemotional difficulties, including alterations in emotion perception. Emotional facial expressions are processed in discrete functional brain modules whose connectivity patterns encode emotion categories, but the involvement of these neural circuits in psychopathology in youth is poorly understood. This study examined the associations between activation and functional connectivity patterns in emotion circuits and psychopathology during development. We used task-based fMRI data from the Philadelphia Neurodevelopmental Cohort (PNC, N = 1221, 8-23 years) and conducted generalized psycho-physiological interaction (gPPI) analyses. Measures of psychopathology were derived from an independent compon

SUBMITTER: Karl V 

PROVIDER: S-EPMC11297301 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature