Cardiovascular mortality in people with cancer compared to the general population: A systematic review and meta-analysis.

ABSTRACT:

Background

Cardiovascular disease (CVD) is the leading cause of non-cancer death in cancer survivors, but the risk of CVD varies between cancers.

Objectives

To synthesise available evidence on patterns and magnitude of CVD mortality risk.

Methods

A systematic search of Medline (OVID), CINAHL and Scopus databases from 01-January-2000 to 16-July-2023 of studies of people with cancer, reporting CVD mortality in cancer population compared with a reference population (e.g. general population) as standardised mortality ratios (SMR). Meta-analysis of SMRs across cancer and CVD types were pooled using a random-effects model to allow for heterogeneity of the true effect size across studies.

Results

We identified 136 studies from 16 countries. Sample sizes ranged from 15

SUBMITTER: Ng HS 

PROVIDER: S-EPMC11297437 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature