Adipose stem cell-derived exosomes in the treatment of wound healing in preclinical animal models: a meta-analysis.

ABSTRACT:

Background

Wound healing has always been a serious issue for doctors and primary health care systems. In addition, adipose stem cell-derived exosomes have been proven to play a positive and effective role in tissue repair and regeneration. A systematic review of these preclinical studies was performed to assess the efficacy of adipose stem cell-derived exosomes (ADSC-Exos) in treating wounds. This article aimed to study the effectiveness of ADSC-Exos for the treatment of animal skin wounds and includes a meta-analysis of exosomes from general wounds and diabetic ulcer wounds in in vitro models of animals to provide a theoretical basis for clinical translation.

Methods

A total of 19 studies with 356 animals were identified by searching the PubMed, Cochrane, MEDLINE Com

SUBMITTER: Wei JT 

PROVIDER: S-EPMC11298109 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature