Regional cerebral oxygen saturation variability and brain injury in preterm infants.

ABSTRACT:

Objective

To examine whether variation of regional cerebral oxygen saturation (rScO₂) within three days after delivery predicts development of brain injury (intraventricular/cerebellar hemorrhage or white matter injury) in preterm infants.

Study design

A prospective study of neonates <32 weeks gestational age with normal cranial ultrasound admitted between 2018 and 2022. All received rScO₂ monitoring with near-infrared spectroscopy at admission up to 72 h of life. To assess brain injury a magnetic resonance imaging was performed at term-equivalent age. We assessed the association between rScO₂ variability (short-term average real variability, rScO_2ARV, and standard deviation, rScO_2SD), mean rScO₂ (rScO_2ME

SUBMITTER: Caleta T 

PROVIDER: S-EPMC11298368 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature