Assessment of 4D flow MRI for quantification of left-to-right shunt in pediatric patients with ventricular septal defect: comparison with right heart catheterization.

ABSTRACT:

Objectives

The percentage of shunt fraction significantly impacts the management of patients with congenital shunts, influencing strategic choices such as surgical or interventional procedures. This study compared the estimated shunt fraction (the ratio of pulmonary-to-systemic flow, Qp/Qs) for quantifying the left-to-right shunt in children with ventricular septal defect (VSD) using heart catheterization, four-dimensional (4D) flow, and two-dimensional (2D) flow magnetic resonance imaging (MRI). The goal was to establish a non-invasive and reliable measurement ratio between pulmonary and systemic blood flow in these patients.

Methods

Between July 2022 and June 2023, patients scheduled to undergo invasive right heart catheterization were included in this study. MRI was perfo

SUBMITTER: Zamani-Aliabadi SM 

PROVIDER: S-EPMC11298441 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature